Clinical experience has shown that the dose of canine distemper virus (CDV) and canine parvovirus (CPV) vaccines can be reduced to 50%, but not more, for small breed type dogs, based on optimum body weight, and still convey the full duration of immunity.
Reducing the volume of vaccine and the number of antigens given together decreases the likelihood of an adverse event. Holistic veterinary medicine is now embracing a new standard of care by reducing the dosage of vaccine depending upon the weight of the pet and other factors.
We are now recruiting 20 small breed adult dogs to participate in a fully funded clinical pilot study. Any adult dog weighing less than 12 pounds that has not been vaccinated for either CDV or CPV in the prior three (3) years is eligible to enroll. There is no charge to the participants.
A signed Informed Consent Form is required from each dog’s owner/guardian, prior to entering the study.
Blood samples will be collected from all 20 enrolled dogs before, 4 weeks after, and 6 months after they have been vaccinated with a half-dose (0.5 ml) of a licensed bi-valent distemper and parvovirus vaccine (Nobivac DPV; Merck Animal Health; available in 25-dose packs.
Richard Palmquist, DVM
Centinela Animal Hospital
721 Centinela Avenue
Inglewood, California 90302